Aldurazyme is a medication that contains laronidase and is used in the treatment of a rare genetic disorder known as metachromatic leukodystrophy (MLD). While Aldurazyme may be a recommended treatment option for MLD, its use should be carefully evaluated by a doctor. It is important to consult a healthcare professional for more information and usage instructions about the medication.
What is Aldurazyme Used For?
Aldurazyme is a medication used as an enzyme replacement therapy. It is used in the treatment of a rare genetic disease called Metachromatic Leukodystrophy. Aldurazyme is used to provide arylsulfatase A enzyme, which is missing in MLD patients. It is important to contact a healthcare professional to learn more about Aldurazyme or any other medication and to have your questions about its usage answered.
How to Use Aldurazyme?
Aldurazyme should be used as directed by a healthcare professional:
Administration Site and Frequency: Aldurazyme is administered intravenously.
Dosage: The dosage may vary depending on factors such as the patient’s age, body weight, and the severity of MLD.
Treatment Duration: Aldurazyme treatment may continue for a lifetime.
Infusion: Aldurazyme is usually given through a vein with a several-hour-long infusion process.
Follow-up and Monitoring: It is important to follow your doctor’s recommendations during the treatment.
Side Effects: Your doctor will provide information about possible side effects during the use of Aldurazyme.
What are the Side Effects of Aldurazyme?
There may be some side effects that may occur during the use of Aldurazyme:
- infusion reactions
- headache, diarrhea
- nausea and vomiting
- cough
- runny nose
- anaphylaxis
- respiratory problems
- heart problems
- increased liver enzymes
- immune response
Does Aldurazyme Interact with Other Medications?
There is no specific interaction known for Aldurazyme with other medications. However, it is important for patients undergoing laronidase treatment to provide their doctors and healthcare professionals with a complete list of the medications they are taking. This is necessary to detect and take appropriate measures for any potential drug interactions. Aldurazyme is generally administered through intravenous infusion and is usually not given in the same vein as other medications. Therefore, the likelihood of interaction with other medications taken through IV is lower. However, your doctor will closely monitor your treatment process to assess and prevent any potential drug interactions.
When Should Aldurazyme Not Be Used?
Aldurazyme should not be used or should be used with caution in certain situations:
Allergy: If you have experienced serious allergic reactions to Aldurazyme or its components in the past, you should not use this medication.
History of Anaphylaxis: If you have a history of a severe allergic reaction called anaphylaxis, you should consult your doctor before using Aldurazyme.
Respiratory Problems: Respiratory problems may occur during the use of Aldurazyme.
Heart Problems: If you have a history of heart problems or risk factors, you should evaluate this condition with your doctor before using Aldurazyme.
Liver Problems: If you have a history of liver disease or elevated liver enzymes, the use of Aldurazyme should be carefully evaluated.
Pregnancy and Breastfeeding: The safety of Aldurazyme during pregnancy or breastfeeding is not fully known.
Other Medical Conditions: If you have any medical conditions or health problems, you should share this information with your doctor and seek their recommendations regarding the use of Aldurazyme.
What Precautions Should Be Taken While Using Aldurazyme?
There are some important points to consider while using Aldurazyme:
Compliance with Doctor’s Instructions: Aldurazyme treatment should be applied as directed by a healthcare professional.
Infusion Process: Aldurazyme is usually administered as an intravenous infusion.
Monitoring Side Effects: It is important to monitor the possible side effects that may occur during the use of Aldurazyme.
Interaction with Other Medications: Discuss with your doctor whether Aldurazyme interacts with other medications.
Allergic Reactions: Allergic reactions may occur while using Aldurazyme.
Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, you should discuss this situation with your doctor before using Aldurazyme.
Regular Follow-up and Check-ups: You should attend regular check-ups recommended by your doctor during the treatment.
Healthy Lifestyle: Maintaining a healthy lifestyle is important during Aldurazyme treatment.
Availability of Aldurazyme in Turkey
Aldurazyme is available in Turkey and is covered by the Social Security Institution (SGK) for reimbursement. The retail selling price of Aldurazyme Infusion Concentrate Solution 100 U/ml 1*5 ml vial is 14,419.55 TL.