Brigatinib, özellikle non-küçük hücreli akciğer kanseri (NSCLC) olan hastaların tedavisinde kullanılan hedefe yönelik bir kanser ilacıdır. ALK pozitif NSCLC hastalarında, gen mutasyonunu hedef alarak kanser hücrelerinin büyümesini ve yayılmasını yavaşlatır veya durdurur. Bir tirozin kinaz inhibitörü olan Brigatinib, özellikle ALK pozitif hastalar için etkili bir tedavi seçeneğidir ve genellikle diğer tedavilere dirençli durumlarda kullanılır. İlaç, oral yoldan alınır ve tedaviye yanıt ile yan etkilere bağlı olarak dozajı ayarlanabilir. Doktor gözetiminde kullanılması gereken Brigatinib, FDA tarafından onaylanmıştır ve kullanımı özel sağlık koşullarına bağlıdır.
What Is Brigatinib Used For?
Brigatinib treats patients with NSCLC. This medication is effective in treating the following conditions:
- ALK positive non-small cell lung cancer
- Patients resistant to other treatments or previously treated patients
How to Use Brigatinib?
Before using Brigatinib, carefully read the instructions your doctor gives you and follow them exactly:
Dosage: Your doctor determines the drug dose and prescribes the appropriate dose for you.
Duration of Use: The duration of Brigatinib treatment may vary depending on the patient’s diagnosis and condition.
Time of Use: Brigatinib is usually taken before meals.
Swallowing the Tablet: Swallow the drug whole with a glass of water.
Missed Doses: If you miss a dose, take it as soon as possible.
Monitor Side Effects: If you feel any side effects or discomfort while using the drug, contact your doctor.
What Are the Side Effects of Brigatinib?
Some people may experience side effects while using Brigatinib:
- headache, loss of appetite
- nausea, vomiting
- abdominal pain, diarrhea
- gas and bloating
- sleep problems, fatigue
- weakness in skeletal muscles
- muscle pain, skin rashes
- allergic reactions
- increase in liver enzymes
Does Brigatinib Interact with Other Drugs?
Brigatinib may interact with some other medications, especially strong inducers or inhibitors:
- antifungal drugs
- HIV medications
- digoxin
- immunosuppressants
- other acid drugs
When Should You Not Use Brigatinib?
Before using Brigatinib, it is important for your doctor to evaluate whether it is a suitable treatment option for you:
Allergy to Brigatinib or Its Other Ingredients: If you have had a serious allergic reaction to Brigatinib or its other components, you should not use this drug.
Drug Interactions: Since Brigatinib can interact with other medications you are taking, your doctor may need to warn you about this.
Liver Problems: If you have severe liver problems or your doctor has diagnosed you with liver disease, using Brigatinib may be risky.
Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, you should discuss the use of Brigatinib with your doctor.
Drug Tolerance: If you have had bad reactions or side effects from previous use of Brigatinib or similar drugs, you may need to avoid using these medications.
Children: Brigatinib is generally not used in children and its use in this age group is not recommended.
Small Intestine Damage: If you have symptoms of the very rare side effect of small intestine damage, you may need to avoid using Brigatinib.
What Should You Pay Attention to While Using Brigatinib?
There are some important points to consider while using Brigatinib:
Follow Doctor’s Instructions: Carefully read and follow the instructions your doctor gives you before using Brigatinib or any medication.
Other Medications and Supplements: If you are considering taking other medications or supplements while using Brigatinib, discuss this with your doctor or pharmacist.
Monitor Side Effects: If you feel any side effects or discomfort while using the drug, contact your doctor.
Doctor Check-Ups: Do not forget to go to check-ups as recommended by your doctor.
Time of Use: Brigatinib is usually taken before meals.
Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the use of Brigatinib with your doctor.
Liver Function: Brigatinib may have an effect on the liver, so people with liver problems should be careful.
Operating Machinery and Driving: Remember that the drug can cause side effects such as dizziness or fatigue.
