Lorviqua is a medication that contains lorlatinib and is used in the treatment of a specific type of cancer, anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC). It targets abnormalities in the ALK gene to inhibit the growth and spread of cancer cells. Lorviqua is a prescription drug and should only be used when evaluated and prescribed by an oncologist or specialist doctor.
Lorviqua: What is it Used For?
Lorviqua is used in the treatment of anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer. It is a tyrosine kinase inhibitor designed to treat ALK-positive NSCLC. This medication works by targeting abnormalities in the ALK gene to inhibit the growth and spread of cancer cells. Lorviqua is typically used in patients who do not respond to or tolerate other ALK inhibitor drugs.
How to Use Lorviqua?
Using Lorviqua involves following a special treatment plan according to your doctor’s prescription instructions and advice:
Follow Your Doctor’s Instructions: Read and carefully follow the instructions recommended by your doctor before starting to use Lorviqua.
Follow the Dosage: Take Lorviqua at the dosage recommended by your doctor.
Swallow the Tablet Whole: Swallow Lorviqua tablets whole with a glass of water.
With or Without Food: Lorviqua can be taken with or without food.
Skip or Missed Dose: If you forget a dose, take it as soon as you remember.
Follow Doctor’s Check-ups: Regularly attend your doctor’s check-ups while using Lorviqua.
Report Side Effects: If you experience any side effects or discomfort while using Lorviqua, inform your doctor immediately.
Other Medications and Supplements: Discuss other medications or supplements with your doctor while using Lorviqua.
What are the Side Effects of Lorviqua?
Below are the common and serious side effects that may occur during the use of Lorviqua:
- headache
- cough
- shortness of breath
- fatigue and weakness
- nausea and vomiting
- diarrhea
- loss of appetite
- dizziness
Using Lorviqua can cause some serious side effects. If you experience these side effects, immediately contact a healthcare professional:
- liver problems
- neurological issues
- lung problems
- abnormal heart rhythm
- bleeding
Does Lorviqua Interact with Other Medications?
Lorviqua should be used with caution as it may interact with other medications:
- Drugs such as Carbamazepine and Phenobarbital
- Liver Enzyme Inhibitors like Ketoconazole
- Liver Enzyme Inducing Drugs like Rifampin
- Antacids or Acid Inhibitors
When Should Lorviqua Not be Used?
Before using Lorviqua, consider the following conditions and you may need to avoid using the medication in these situations:
Hypersensitivity or Allergy: If you have hypersensitivity or allergy to Lorviqua or any of its components, you should not use the medication.
Liver Problems: Those with severe liver disease or a history of liver problems should inform their doctors before using Lorviqua.
Pregnancy and Breastfeeding: Lorviqua should not be used during pregnancy or breastfeeding.
Severe Neurological Problems: Severe neurological problems may occur during Lorviqua use, so if you have neurological problems such as loss of consciousness or balance issues, you should not use the medication.
Drug Interactions: Lorviqua can interact with other drugs, and these interactions can sometimes be serious.
Constipation and Diarrhea Issues: The use of Lorviqua can worsen digestive system problems such as constipation or severe diarrhea.
Previous Drug Tolerance: If you have previously had a negative response or intolerance to Lorviqua or similar drugs, you may need to avoid using this medication.
Birth Control Pills: Lorviqua can reduce the effectiveness of birth control pills.
What Precautions Should be Taken While Using Lorviqua?
While using Lorviqua, pay attention to the following important points:
Follow Your Doctor’s Instructions: Use Lorviqua only as prescribed by your doctor and according to their instructions.
Follow the Dosage: Take Lorviqua at the same time every day and do not exceed or reduce the recommended dosage by your doctor.
Swallow the Tablet Whole: Swallow Lorviqua tablets whole with a glass of water.
Regular Check-ups: You should regularly attend check-ups as determined by your doctor.
Report Side Effects: If you experience any side effects or discomfort while using Lorviqua, inform your doctor immediately.
Liver Health: Your liver enzymes will be regularly monitored while using Lorviqua.
Other Medications and Supplements: Discuss other medications or supplements with your doctor while using Lorviqua.
Pregnancy and Birth Control: Lorviqua should not be used during pregnancy.
Driving and Operating Machinery: Lorviqua can cause dizziness or drowsiness.
Health Condition and Other Issues: Share your current health condition and other medications with your doctor while using Lorviqua.
Availability of Lorviqua in Turkey
Lorviqua is available in Turkey and is covered by the Social Security Institution (SGK) for reimbursement. The retail price for Lorviqua Film Coated Tablet 25 mg in a package of 30 tablets is 19,513.95 TL, and the retail price for Lorviqua Film Coated Tablet 100 mg in a package of 30 tablets is 66,451.82 TL.
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