Spravato is a medication that contains esketamine and is used in the treatment of depression. It is particularly used in patients with treatment-resistant major depressive disorder who do not respond to other antidepressant treatments. Unlike commonly taken antidepressants, Spravato is applied as a nasal spray. The use of Spravato should be done under the supervision of a healthcare professional, and individuals considering this treatment should have a detailed discussion with their doctors, especially regarding its side effects and risks. Spravato has side effects and potential risks and should be carefully monitored. Therefore, the use or initiation of this medication should be carefully evaluated and only done under appropriate circumstances and under the supervision of a doctor.
Spravato: What is it Used For?
Spravato is primarily used to alleviate the symptoms of treatment-resistant major depressive disorder. It offers an alternative approach in the treatment of major depressive disorder and has the potential to rapidly alleviate depression symptoms. The use of Spravato should be done under the supervision of a healthcare professional, and individuals considering the treatment should have a detailed discussion with their doctors about its side effects and risks. This medication is considered as an option for individuals who do not benefit from traditional antidepressant treatments, and the treatment plan should be personalized for each patient.
How to Use Spravato?
The use of Spravato should be done according to your doctor’s prescription and instructions:
Doctor Supervision: The use of Spravato should be done under the supervision of a healthcare professional.
Nasal Spray: Spravato is applied as a nasal spray.
Dosage: The dosage of Spravato is determined by your doctor and applied according to the prescription.
Application Duration: A dose of Spravato application generally takes a few minutes.
Observation: After the medication is applied, a healthcare professional will observe you for a while.
Driving and Machine Use: After using Spravato, you should refrain from driving or operating hazardous machinery for a while.
Treatment Plan: The Spravato treatment plan will be determined by your doctor.
What are the Side Effects of Spravato?
The use of Spravato can cause some side effects:
- dissociation
- dizziness or feeling lightheaded
- fatigue or weakness
- nausea or vomiting
- headache, loss of appetite
- anxiety, diarrhea
- high blood pressure, increased sweating
- increased heart rate
- blurred vision
- drowsiness or tingling sensation
- abnormal sensations or taste changes
- facial flushing or skin reactions
Does Spravato Interact with Other Medications?
Spravato can interact with other medications:
- Sedatives or Depressants
- MAO Inhibitors
- Other Psychiatric Medications
When Should Spravato Not Be Used?
There are some situations in which Spravato should not be used or should be used with caution:
Allergy to Medications: If you have a known allergy to esketamine or other medication ingredients, you should not use Spravato.
Family or Personal History: If you or your family have a history of bipolar disorder, severe anxiety, psychotic disorder, or any other psychiatric condition, you should evaluate this condition with your doctor before using the medication.
Blood Clots and Thromboembolic Disease: If you have previously experienced venous thromboembolic disease or are at risk of thromboembolic disease, you should discuss this condition with your doctor before using the medication.
High Blood Pressure: If you have high blood pressure or have treated high blood pressure, you should evaluate this condition with your doctor before using the medication.
Liver Problems: If you have severe liver problems, you should discuss this condition with your doctor before using the medication.
Risk of Substance Abuse: Individuals with a history or risk of substance abuse should avoid the use of Spravato.
Pregnancy and Breastfeeding: Those who are pregnant or breastfeeding should discuss the potential risks and benefits of the medication during these periods with their doctors.
Other Medications: Spravato may interact with other medications or have potential risks.
What Precautions Should Be Taken While Using Spravato?
There are some important points to consider while using Spravato:
Compliance with Doctor’s Instructions: You should only use Spravato as recommended by your doctor and in the prescribed dosage.
Supervised Use: Spravato is administered under the supervision of a healthcare professional in a healthcare facility or clinical setting.
Driving and Machine Operation: After using Spravato, you should refrain from driving or operating hazardous machinery for a while.
Dissociation and Perception Changes: Dissociation experiences may occur during the use of Spravato, which may involve emotional and mental experiences such as detachment from reality or changes in perception.
Monitoring of Side Effects: While using the medication, you should inform your doctor about any side effects or discomfort.
Alcohol and Drug Interactions: Alcohol or other drugs may interact with Spravato, leading to unwanted side effects.
Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, you should evaluate the potential risks and benefits of the medication during these periods with your doctor.
Other Medications: Spravato may interact with other medications. If you are using or considering using other medications, you should discuss their interactions with your doctor.
Availability of Spravato in Turkey
Spravato is available in Turkey but is not covered by the Social Security Institution (SGK) reimbursement. The retail price for Spravato Nasal Spray, Solution 28 mg, 2-pack is 6492.01 TL, and the retail price for Spravato Nasal Spray, Solution 28 mg, 3-pack is 9695.82 TL.
