Cisplatin is a powerful chemotherapy drug used in cancer treatment. It binds to DNA to prevent cell proliferation, thereby stopping the growth of cancer cells. Cisplatin is commonly used to treat various types of cancer, especially testicular, ovarian, bladder, and lung cancers. However, due to its potential for serious side effects, its use requires careful monitoring. This drug is usually administered by specialized healthcare personnel in hospitals or chemotherapy centers. The dosage and duration of treatment depend on the patient’s specific health condition and response to the treatment.
What Is Cisplatin Used For?
Cisplatin is used to treat various types of cancer:
- testicular cancer
- ovarian cancer
- bladder cancer
- lung cancer
- head and neck cancers
- esophageal cancer
How to Use Cisplatin?
Before using Cisplatin, carefully read and follow the instructions given by your doctor or healthcare professional:
Dosage: Your doctor determines the Cisplatin dose, usually calculated based on body surface area.
Method of Administration: Cisplatin is administered intravenously (IV), meaning through a vein.
Duration of Treatment: The duration of Cisplatin treatment varies depending on the type of cancer and the response to the treatment.
Treatment Cycles: Cisplatin is typically administered at specific intervals (e.g., every 3-4 weeks).
Hydration: Adequate fluid intake before and after Cisplatin treatment is essential to prevent kidney damage, usually given via intravenous fluids.
Monitor Side Effects: If you experience any side effects or discomfort while using the drug, contact your doctor.
What Are the Side Effects of Cisplatin?
Some individuals may experience side effects while using Cisplatin:
- nausea, vomiting
- kidney damage
- hearing loss
- nerve damage
- diarrhea or constipation
- electrolyte imbalances
- bone marrow suppression
- allergic reactions
Does Cisplatin Interact with Other Drugs?
Cisplatin can interact with other drugs:
- aminoglycoside antibiotics
- diuretics
- other chemotherapy drugs
- immunosuppressive drugs
- anti-emetic drugs
When Should Cisplatin Not Be Used?
Before using Cisplatin, your doctor must evaluate whether it is an appropriate treatment option for you:
Allergy to Cisplatin or its other components: If you have a history of allergic reactions to Cisplatin or its ingredients, you should not use this drug.
Kidney dysfunction: Because Cisplatin can damage the kidneys, individuals with kidney dysfunction should not use this drug.
Hearing problems: Due to the risk of hearing loss, Cisplatin use is risky for individuals with existing hearing issues.
Bone marrow suppression: Cisplatin can cause bone marrow suppression, so it is not suitable for individuals already experiencing this condition.
Pregnancy and breastfeeding: If you are pregnant or breastfeeding, you should discuss Cisplatin use with your doctor.
Other severe health issues: Special caution is required, especially in cases of heart disease or liver dysfunction.
What to Pay Attention to While Using Cisplatin?
There are some important points to consider while using Cisplatin:
Follow Doctor’s Instructions: Before using Cisplatin or any drug, carefully read and follow your doctor’s instructions.
Other Medications and Supplements: If you plan to take other medications or supplements while using Cisplatin, discuss this with your doctor or pharmacist.
Monitor Side Effects: If you experience any side effects or discomfort while using the drug, contact your doctor.
Doctor Visits: Do not forget to attend regular check-ups as recommended by your doctor.
Kidney Function: Since Cisplatin can affect kidney functions, regular kidney function tests are necessary.
Hearing Tests: Regular hearing tests may be needed to monitor for hearing loss.
Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, you should discuss Cisplatin use with your doctor.
Nausea and Vomiting: Use the medications prescribed by your doctor to prevent nausea and vomiting as directed.